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US 6,440,405 B1Granted
Quaternary ammonium functionalized dendrimers and methods of use therefor
AssigneeUniversity of Delaware
InventorsStuart L. Cooper, Chris Zhisheng Chen
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Abstract
Quaternary ammonium functionalized dendrimers are described which are suitable for controlling the growth of microorganisms. The quaternary ammonium functionalized dendrimer biocides of the present invention are effective against a wide variety of microbial species including bacteria, spores, yeast, fungi, mold and multicellular microorganisms.
Claims28
A quaternary ammonium functionalized dendrimer of the formula:
- wherein
- D is a dendrimer;
- n is the generation number of the functionalized dendrimer selected from the group consisting of 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, and 15;
- z is an integer less than or equal to 2(n+1);
- x is an anion;
- R is a linking group;
- Y is an alkyl group having 1 to 32 carbon atoms, an aryl group having 1 to 32 carbon atoms, or chloromethyl;
- A is an alkyl group having 1 to 32 carbon atoms, an aryl group having 1 to 32 carbon atoms, or chloromethyl;
- and
- B is an alkyl group having 1 to 32 carbon atoms, an aryl group having 1 to 32 carbon atoms, or chloromethyl.
7 more elements
A quaternary ammonium functionalized dendrimer of Formula I wherein D is an NH2 terminated polypropylene imine (PPI) dendrimer.
A method of controlling the growth of a microorganism comprising:
- exposing said microorganism to a quaternary ammonium functionalized dendrimer of formula I wherein
- D is a dendrimer;
- n is the generation number of the functionalized dendrimer selected from the group consisting of 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, and 15;
- z is an integer less than or equal to 2(n+1);
- x is an anion;
- R is a linking group;
- Y is an alkyl group having 1 to 32 carbon atoms, an aryl group having 1 to 32 carbon atoms, or chloromethyl;
- A is an alkyl group having 1 to 32 carbon atoms, an aryl group having 1 to 32 carbon atoms, or chloromethyl;
- and
- B is an alkyl group having 1 to 32 carbon atoms, an aryl group having 1 to 32 carbon atoms, or chloromethyl.
7 more elements
Dependencies are inferred from the claim text.