Chromatography resin support
AssigneeWestinghouse Savannah River Company
InventorJames G. Dobos
Life of this patent
Estimating the term…
Abstract
An apparatus and method of using an improved chromatography resin support is disclosed. The chromatography support platform is provided by a stainless steel hollow cylinder adapted for being inserted into a chromatography column. An exterior wall of the stainless steel cylinder defines a groove for carrying therein an “O”-ring. The upper surface of the stainless steel column is covered by a fine stainless steel mesh welded to the edges of the stainless steel cylinder. When placed upon a receiving ledge defined within a chromatography column, the “O”-ring provides a fluid tight seal with the inner edge wall of the chromatography cylinder. The stainless steel mesh supports the chromatography matrix and provides a back flushable support which is economical and simple to construct.
Claims8
A resin support apparatus for a chromatography column comprising:
- a stainless steel cylinder having an outer diameter and an inner diameter, the outer diameter being greater than a height of the stainless steel cylinder, the cylinder defining a groove in an exterior wall of the stainless steel cylinder, the groove being substantially parallel to an upper and a lower rim of the stainless steel cylinder;
- an “O”-ring positioned within the groove, the “O”-ring having an outer diameter greater than the outer diameter of the stainless steel cylinder;
- and,
- a stainless steel mesh welded to an upper surface of the stainless steel cylinder and covering an opening defined by the stainless steel cylinder;
- wherein, when said stainless steel cylinder is placed within a receiving surface formed on an interior surface of a volumetric cylinder, the “O”-ring provides a fluid tight seal between the stainless steel cylinder and the inner wall of the volumetric cylinder, the stainless steel mesh providing a support platform adapted for receiving a supply of a chromatography matrix.
A chromatography column comprising
- a stainless steel cylinder having an outer diameter and an inner diameter, the outer diameter being greater than a height of the stainless steel cylinder, the cylinder defining a groove in an exterior wall of the stainless steel cylinder, the groove being substantially parallel to an upper and a lower rim of the stainless steel cylinder;
- an “O”-ring positioned within the groove, the “O”-ring having an outer diameter greater than the outer diameter of the stainless steel cylinder;
- and,
- a stainless steel mesh welded to an upper surface of the stainless steel cylinder and covering an opening defined by the stainless steel cylinder;
- a volumetric cylinder having an interior surface, said interior surface further defining a receiving surface and engaging a bottom of said stainless steel cylinder, said “O” ring engaging a portion of said interior surface of said volumetric cylinder in a fluid-tight seal;
- wherein said stainless steel mesh and said stainless steel cylinder provide a support platform adapted for receiving a supply of a chromatography matrix.
Dependencies are inferred from the claim text.