US 6,426,066 B1 · Use of physiologically balanced, ionized, acidic solution in wound healing

Abstract

A physiologically-balanced, ionized, acidic solution. The solution may be prepared by the electrolysis of a solution comprising a mixture of inorganic salts in physiologically balanced proportions. A mixture of inorganic salts and, optionally, minerals (such as metallic elements, for example, and not by way of limitation) is used in order to mimic the electrolyte concentration and mixture of body fluid in an isotonic state. The solution typically comprises halide salts of sodium, potassium, calcium, and other cations. Typically the halide is fluoride, chloride, bromide, or iodide; and most typically chloride. The halide-comprising acidic solution is physiologically balanced by the inclusion of elements such as sodium, potassium, magnesium, zinc, lithium, and beryllium in the solution. The composition of the invention is nontoxic and has antibacterial properties. The composition is useful in any application in which antimicrobial properties are desirable, particularly in the topical application to wounds, burns, etc., and can be incorporated into a bandage or wound dressing.

Claims15

Dependent claims

A method of promoting wound healing, or tissue repair, or tissue regeneration, in a subject in need of such treatment comprising:

applying to a wound, or a damaged tissue, or a combination thereof, with an effective amount of a physiologically-balanced, acidic composition comprising an electrolyzed aqueous solution of halide-comprising salts including about 0.3 to about 14 g/L sodium halide, about 0.02 to about 0.8 g/L potassium halide, and about 0.01-0.5 g/L magnesium halide;
and having a total concentration of halide-comprising salts in the range of about 0.4 g/L to about 16 g/L, a pH ranging from about 2 to about 6, an oxidation reduction potential ranging from about +600 mV to about +1200 mV;
a titratable halide content ranging from about 20 ppm to about 100 ppm;
an O3 concentration ranging from about 0.001 ppm to about 5 ppm;
an O2 concentration ranging from about 5 ppm to about 30 ppm;
and, a HClO concentration ranging from about 0.1 ppm to about 1000 ppm.

3 more elements

A method of promoting wound healing, or tissue repair, or tissue regeneration in a subject in need of such treatment, comprising:

applying to a wound, or a damaged tissue, or a combination thereof with an effective amount of a physiologically-balanced, acidic composition comprising an electrolyzed aqueous solution of salts, including sodium cations at a concentration of about 0.005 to about 7 g/L, potassium cations at a concentration of about 0.005 to about 0.6 g/L, and magnesium cations at a concentration of about 0.005 to about 0.1 g/L;
and, a pH ranging from about 2 to about 6, an oxidation reduction potential ranging from about +600 mV to about +1200 mV;
an O3 concentration ranging from about 0.001 ppm to about 5 ppm;
an O2 concentration ranging from about 5 ppm to about 30 ppm;
and, a HClO concentration ranging from about 0.1 ppm to about 1000 ppm.

2 more elements

Dependencies are inferred from the claim text.

Use of physiologically balanced, ionized, acidic solution in wound healing

Life of this patent

Use of physiologically balanced, ionized, acidic solution in wound healing

Life of this patent

Abstract

Claims15