Systems for delivering anti-infective compositions to treat disordered tissue such as cold sores
OwnerB. Ron Johnsoninventor
Life of this patent
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Abstract
The present invention relates to the treatment of disordered epithelial tissues such as cold sores and other complications resulting from disorders such as herpes, and the like. The invention relates to the use of an anti-infective and/or antimicrobial active agent in a carrier, with vigorous agitation of the disordered epithelial tissue for topical treatment thereof under such conditions sufficient to achieve clinically discernable improvement of the disordered epithelial tissue. The preferred anti-infective and/or antimicrobial active agent is an organohalide such as a quaternary ammonium compound, preferably benzalkonium chloride. The inventive method may be used also in connection with a preferred applicator configuration.
Claims62
A system for treating disordered tissue such as a cold sore treatment site, the system comprising:
- a treatment composition for application to and penetration into the disordered tissue, the composition comprising at least one anti-infective agent in a carrier,
- the at least one anti-infective agent comprising an organohalide,
- wherein the treatment composition is a liquid, said liquid comprising a tissue penetrating component for penetrating skin in a rapid manner without rapidly diffusing beyond the skin;
- and
- an applicator to deliver the treatment composition into the disordered tissue.
A system for treating disordered tissue such as a cold sore treatment site, the system comprising:
- a treatment composition for application to and penetration into the disordered tissue, the treatment composition comprising at least one benzalkonium chloride compound in a carrier,
- wherein the carrier comprises a mixture of isopropyl alcohol and water,
- wherein the treatment composition is a liquid, said liquid comprising a tissue penetrating component for penetrating skin in a rapid manner without rapidly diffusing beyond the skin, and
- an applicator comprising:
- a reservoir for holding the treatment composition,
- a flexible container around the reservoir for holding the reservoir in a manner such that compression of the flexible container causes the reservoir to release the treatment composition into the flexible container, the flexible container having a closed end opposite to an open delivery end, and
- an agitation pad in the open delivery end of the flexible container,
- wherein the agitation pad has a retention portion within the flexible container and a delivery portion that extends beyond the open delivery end of the flexible container and wherein the delivery portion terminates at an agitation surface.
A system for treating disordered tissue such as a cold sore treatment site, the system comprising:
- a treatment composition for application to and penetration into the disordered tissue, the composition comprising at least one anti-infective agent in a carrier, said carrier comprising an alcohol and water,
- wherein the at least one anti-infective agent comprises an organohalide,
- wherein the treatment composition is a liquid that is void of penetration inhibiting components, said liquid comprising a tissue penetrating component for rapidly penetrating skin without rapidly diffusing beyond the skin,
- wherein the treatment composition is substantially oil free such that there is essentially no residue remaining that is visibly detectable to any substantial degree after the treatment composition has been applied and absorbed;
- and
- an applicator comprising:
- a reservoir for holding the treatment composition,
- a flexible container for holding the reservoir in a manner such that compression of the flexible container causes the reservoir to release the treatment composition into the flexible container, the flexible container having a closed end opposite to an open delivery end, and
- an agitation pad at the open delivery end of the flexible container,
- wherein the agitation pad has a treatment composition delivery portion.
Dependencies are inferred from the claim text.