Methylidene malonate nanoparticles
AssigneeVirsol
InventorsNicole Bru-Magniez, Xavier Guillon, Pascal Breton, Patrick Couvreur, François Lescure, Claude Roques-Carmes, Gérard Riess
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Abstract
Nanoparticles formed from a random polymer of at least one compound of formula (I) in which A represents a group or a group; R1 and R2, identical or different, represent a linear or branched C1-C6 alkyl group; n=1, 2, 3, 4 or 5, having a diameter of less than 500 nm and an average molecular mass (Mw) between about 8000 and 100000, the nanoparticles being formed from homogeneous molecular species, and optionally containing a biologically active material.
Claims24
Nanoparticles formed from a random polymer of at least one compound of formula (I)
- in which
- A represents a
- group or a
- group;
- R1 and R2, identical or different, represent a linear or branched C1-C6 alkyl group;
- n=1, 2, 3, 4 or 5,
- having a diameter of less than 500 nm and an average molecular mass (Mw) between about 8000 and 100000, said nanoparticles being formed from homogeneous molecular species.
Nanoparticles formed from a polymer of formula (I)
- in which
- A represents a
- group or a
- group;
- R1 and R2, identical or different, represent a linear or branched C1-C6 alkyl group;
- n=1, 2, 3, 4 or 5,
- having a diameter of less than 500 nm and an average molecular mass (Mw) between about 8000 and 100000, said nanoparticles being formed from homogeneous molecular species.
Nanoparticles formed from a random polymer of at least one compound of formula (I)
- in which
- A represents a
- group or a
- group;
- R1 and R2, identical or different, represent a linear or branched C1-C6 alkyl group;
- n=1, 2, 3, 4 or 5,
- having a diameter of less than 500 nm and an average molecular mass (Mw) between about 8000 and 100000, said nanoparticles being formed from homogeneous molecular species and obtained by a method comprising the steps of dissolving said at least one compound of formula (I) in a water-miscible aprotic organic solvent, and mixing the dissolved at least one compound of formula (I) with an aqueous polymerization medium, resulting in a non-solvent mixture of the polymer formed.
Dependencies are inferred from the claim text.