Methods and apparatus for synthesizing labeled combinatorial chemistry libraries
AssigneeDiscovery Partners International, Inc.
InventorsJohn Cargill, Robert W. Armstrong
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Abstract
The present invention provides labeled synthetic libraries of random oligomers and methods and apparatus for generating labeled synthetic oligomer libraries. Each member of such a library is labeled with a unique identifier tag that specifies the structure or sequence of the oligomer. In a preferred embodiment of the present invention the identifier tag is a microchip that is pre-encoded or encodable with information that is related back to a detector when the identifier tag is pulsed with electromagnetic radiation.
Claims22
A device for tracking synthesis of a library member of a combinatorial library, the device comprising:
- a synthesis support having a surface adapted for linking to a first monomer;
- an identifier tag disposed within or linked to the synthesis support, the identifier tag comprising encoded information readable by a radiofrequency scanner or barcode scanner that is unique to the synthesis support and means for scanning the identifier tag, wherein, when a first monomer is linked to the synthesis support, the first monomer and any oligomer synthesized using the first monomer is identified.
Dependencies are inferred from the claim text.