US 6,409,972 B1 · Prepackaged liquid bone cement

Abstract

Poly(alkyl methacrylate) bone cement ingredients are prepackaged as two separate components in two separate chambers of a container which can be connected to a static mixer, where both components are in a liquid form that is at least substantially air-free, and wherein the static mixer can mix the two liquid components without mechanical agitation and without the introduction of air into the two liquid components during the transfer of the two liquid components from their separate chambers through the static mixer. The first liquid component is formed by premixing a bone cement liquid monomer with bone cement polymer powder, a polymerization initiator, and a stabilizer to form a liquid mixture. The second liquid component is formed by premixing bone cement liquid monomer with bone cement polymer powder, if any, a stabilizer, and an activator to form a liquid mixture. The monomer/polymer ratio of each liquid component containing polymer will be in the range of the minimum required to provide the respective component as a liquid mixture up to the maximum which, when the two liquid components are mixed, will result in the desired monomer/polymer ratio for the mixture. Each end of each of the chambers can be provided with an air impermeable layer to provide a hermetic seal for the chamber.

Claims20

Dependent claims

A bone cement preparation system for providing a liquid bone cement having a first monomer/polymer ratio, said system comprising a container having a first end and a second end, said container having a first chamber and a second chamber located between said first and second ends, each of said first and second chambers having an outlet in said second end of said container, said container being free of internal communication between said first chamber and said second chamber;

said first chamber containing a first liquid component for said liguid bone cement, said first liquid component comprising a liquid alkyl methacrylate, poly(alkyl methacrylate), a polymerization initiator, and a stabilizer for preventing spontaneous polymerization of the liquid alkyl methacrylate in said first liquid component, the liquid alkyl methacrylate being present in said first liquid component in an amount which is at least sufficient to provide the first liquid component as a liquid mixture, said first chamber being at least substantially free of air;
said second chamber containing a second liquid component for said liquid bone cement, said second liquid component comprising a liquid alkyl methacrylate, an activator, and a stabilizer for preventing spontaneous polymerization of the liquid alkyl methacrylate in said second liquid component, the liquid alkyl methacrylate being present in said second liquid component in an amount which is at least sufficient to provide the second liquid component as a liquid mixture, said second chamber being at least substantially free of air.

A bone cement preparation system for providing a liquid bone cement having a first monomer/polymer ratio, said system comprising a container having a first end and a second end, said container having a first compartment and a second compartment located between said first and second ends, each of said first and second compartments having a longitudinal axis, each of said first and second compartments having an outlet in said second end of said container, said container being free of internal communication between said first compartment and said second compartment;

a first piston positioned in said first compartment to form a first chamber between said first piston and the outlet of said first compartment;
a second piston positioned in said second compartment to form a second chamber between said second piston and the outlet of said second compartment;
said first chamber containing a first liquid component for said liquid bone cement, said first liquid component comprising a liquid alkyl methacrylate, a polymerization initiator, a stabilizer for preventing spontaneous polymerization of the liquid alkyl methacrylate in said first liquid component, and poly(alkyl methacrylate) which was in powder form prior to inclusion in said first liquid component, the liquid alkyl methacrylate being present in said first liquid component-in an amount which is at least sufficient to provide the first liquid component as a liquid mixture, said first chamber being at least substantially free of air;
said second chamber containing a second liquid component for said liquid bone cement, said second liquid component comprising a liquid alkyl methacrylate, an activator, and a stabilizer for preventing spontaneous polymerization of the liquid alkyl methacrylate in said second liquid component, the liquid alkyl methacrylate being present in said second liquid component in an amount which is at least sufficient to provide the second liquid component as a liquid mixture, said second chamber being at least substantially free of air.

1 more element

Dependencies are inferred from the claim text.

Prepackaged liquid bone cement

Life of this patent

Prepackaged liquid bone cement

Life of this patent

Abstract

Claims20