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US 6,405,732 B1Granted
Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors
AssigneeCuron Medical, Inc.
InventorsStuart D. Edwards, John Gaiser, David S. Utley
Life of this patent
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Abstract
A method of treating a sphincter provides a sphincter electropotential mapping device with at least one of a mapping electrode or a treatment electrode. The sphincter electropotential mapping device is introduced into at least a portion of the sphincter, the lower esophageal sphincter, stomach, the cardia or the fundus. Bioelectric activity causing a relaxation of the sphincter is detected and energy is delivered from either the mapping electrode or the treatment electrode to treat the bioelectric activity.
Claims49
A method of treating a sphincter, comprising:
- providing a sphincter electropotential mapping device with at least one of a mapping electrode or a treatment electrode;
- introducing the sphincter electropotential mapping device into at least a portion of one of the sphincter, a lower esophageal sphincter, a stomach, a cardia or a fundus;
- detecting a electrical activity causing a transient relaxation of the sphincter;
- and
- delivering energy from one of the mapping electrode or the treatment electrode to treat the electrical activity.
2 more elements
A method of treating a sphincter, comprising:
- providing a sphincter treatment device with at least one of a mapping electrode or a treatment electrode;
- introducing the sphincter electropotential mapping device into at least a portion of one of the sphincter, a lower esophageal sphincter, a stomach, a cardia or a fundus;
- stimulating one of the sphincter, the lower esophageal sphincter, the stomach, the cardia or the fundus to produce a transient relaxation of the sphincter;
- and
- identifying a portion of one of the sphincter, the lower esophageal sphincter, the stomach, the cardia or the fundus causing a transient relaxation of the sphincter;
- and
- delivering energy from the sphincter electropotential mapping device to treat the portion of one the sphincter, the lower esophageal sphincter, the stomach, the cardia or the fundus causing the transient relaxation of the sphincter.
4 more elements
A method of treating a sphincter, comprising:
- providing a sphincter electropotential mapping device with a mapping electrode or a treatment electrode;
- introducing the sphincter electropotential mapping device into at least a portion of one of the sphincter, a lower esophageal sphincter, a stomach, a cardia or a fundus;
- detecting a bioelectric activity causing a transient relaxation of the sphincter;
- providing a sphincter treatment apparatus with a treatment energy delivery device;
- introducing the sphincter treatment apparatus into at least a portion of one of the sphincter, a lower esophageal sphincter, a stomach, a cardia or a fundus;
- and
- delivering energy from the treatment energy delivery device to treat the bioelectric activity.
4 more elements
A method of treating a sphincter, comprising:
- providing a gastroesophageal sensing device with a stimulating electrode or a mapping electrode;
- introducing the gastroesophageal sensing device into a portion of the upper gastroesophageal tract;
- stimulating a portion of the upper gastroesophageal tract to produce one of a swallowing reflex, peristaltic wave or a relaxation of the lower esophageal sphincter;
- observing for a swallowing reflex, a peristaltic wave or a relaxation of a lower esophageal sphincter;
- providing a sphincter electropotential treatment device with a mapping electrode or a treatment electrode;
- introducing the sphincter electropotential treatment device into at least a portion of one of the esophagus, a lower esophageal sphincter, a stomach, a cardia or a fundus;
- treating one of the esophagus, the lower esophageal sphincter, the stomach, the cardia or the fundus;
- restimulating the portion of the upper gastroesophageal tract to produce one of the swallowing reflex, the peristaltic wave or the relaxation of the lower esophageal sphincter;
- and
- observing for the swallowing reflex, the peristaltic wave or the relaxation of the lower esophageal sphincter.
7 more elements
A method of treating a sphincter, comprising:
- providing a sphincter treatment device having an elongated member, the elongated member including at least one of a stimulating electrode, a mapping electrode or a treatment electrode, the stimulating electrode positioned proximally to one of the mapping electrode or the treatment electrode;
- introducing the sphincter treatment device into at least a portion of one of the esophagus, a lower esophageal sphincter, a stomach, a cardia or a fundus;
- stimulating a portion of the upper gastroesophageal tract to produce one of a swallowing reflex, a peristaltic wave or a relaxation of the lower esophageal sphincter;
- observing for a swallowing reflex, a peristaltic wave or a relaxation of a lower esophageal sphincter;
- treating one of the esophagus, the lower esophageal sphincter, the stomach, the cardia or the fundus;
- restimulating the portion of the upper gastroesophageal tract to produce one of the swallowing reflex, the peristaltic wave or the relaxation of the lower esophageal sphincter;
- and
- observing for the swallowing reflex, and the peristaltic wave or the relaxation of the lower esophageal sphincter.
5 more elements
Dependencies are inferred from the claim text.