US 6,403,970 B1Granted

Matrix biochip sensing system

AssigneeIndustrial Technology Research Institute

InventorLung-Yu Hung

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Abstract

The matrix biochip sensing system of this invention uses a low-cost LED (light emit diode) matrix as the light source for the sensing system. The matrix biochip sensing system comprises an LED matrix light source, a biochip clamping member, an optical information filter module, an optical lens array, an optical sensor and a signal processing and control module. The light spots of the LED matrix is turned on in sequence, such that the fluorescent spots of the biochip that are respectively corresponding to the light spots of the laser diodes matrix may be actuated in the same sequence. Fluorescent spots so actuated are focused to a single optical sensor through an optical lens. At each sensing cycle of the optical sensor, only one fluorescent spot may be actuated. The output of the optical sensor in combination of the time axis may be processed by the signal processing and control module to obtain the genetic signals of the biochip.

Claims5

Dependent claims

A matrix biochip sensing system, comprising:

a matrix light source comprising a plurality of light generating spots arranged in a matrix wherein each light generating spot generates a light independently;
a biochip clamping element, positioned in the downstream position relative to said matrix light source to position a biochip comprising a matrix distribution, wherein each spot of said matrix distribution of said biochip is spatially corresponding to one light generating spot of said matrix light source;
an optical sensor to sense light power of respective spots of said matrix distribution of said biochip, after being actuated by light generated by said light generating spot of said matrix light source;
and
an optical signal processing and control module to control light generating from respective light generating spots of said matrix light source whereby only one light generating spot generates light during one working cycle, and to record time of light generation and light power as sensed by said optical sensor.

2 more elements

Dependencies are inferred from the claim text.