Integrated portable biological detection system
AssigneeNanogen, Inc.
InventorsJing Cheng, Lei Wu, Michael J. Heller, Ed Sheldon, Jonathan Diver, James P. O'Connell, Dan Smolko, Shila Jalali, David Willoughby
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AssigneeNanogen, Inc.
InventorsJing Cheng, Lei Wu, Michael J. Heller, Ed Sheldon, Jonathan Diver, James P. O'Connell, Dan Smolko, Shila Jalali, David Willoughby
Estimating the term…
We have performed separation of bacterial and cancer cells from peripheral human blood in microfabricated electronic chips by dielectrophoresis. The isolated cells were examined by staining the nuclei with fluorescent dye followed by laser induced fluorescence imaging. We have also released DNA and RNA from the isolated cells electronically and detected specific marker sequences by DNA amplification followed by electronic hybridization to immobilized capture probes. Efforts towards the construction of a “laboratory-on-a-chip” system are presented which involves the selection of DNA probes, dyes, reagents and prototyping of the fully integrated portable instrument.
An integrated system for the analysis of eukaroytic and/or prokaryotic cells in a biological sample comprising:
An integrated system for the analysis of a biological sample containing eukaryotic and/or prokaryotic cells, comprising:
An integrated system for the analysis of a biological sample containing eukaroytic and/or prokaryotic cells, comprising:
Dependencies are inferred from the claim text.