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US 6,397,849 B1Granted
Methods of ophthalmic administration
AssigneeInsite Vision Incorporated
InventorsLyle M. Bowman, James F. Pfeiffer, Leslie A. Clark, Karl I. Hecker
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AssigneeInsite Vision Incorporated
InventorsLyle M. Bowman, James F. Pfeiffer, Leslie A. Clark, Karl I. Hecker
Estimating the term…
Intrascleral injection of a therapeutic or diagnostic material at a location overlying the retina provides a minimally invasive technique for delivering the agent to the posterior segment of the eye. The procedure also allows for close proximity of the material to the targeted site and can be effectively used to treat conditions associated with the posterior segment of the eye, including macular degeneration, vein occlusion, and diabetic retinopathy. The sclera can be used to hold a depot of the material such as for sustained released or as a conduit for propelling material through whereby the material is delivered immediately to the underlying tissues but without physically penetrating the sclera with an instrument or otherwise unreasonably traumatizing the eye.
A method of intrascleral injection, which comprises:
A method for treating ocular tissue, which comprises:
A method for treating macular degeneration, which comprises injecting an effective macular degeneration treating amount of a macular degeneration treating material into the sclera over the posterior segment of an eye in need of treatment thereof through a location on the exterior surface of the sclera that overlies retinal tissue.
A method for treating a condition in the eye involving neovascularization, which comprises injecting into the sclera over the posterior segment of an eye, through a location on the exterior surface of the sclera that overlies retinal tissue, an effective neovascularization reducing or preventing amount of an anti-angiogenesis agent.
A method of intrascleral injection, comprising:
Dependencies are inferred from the claim text.