Methods and compositions for combating HIV infection
AssigneeRibotargets, Ltd.
InventorsJonathan Karn, Rodney Warren Zemmel, Peter Jonathan Gasking Butler, Roger K. Craig, Alistair Simpson Irvine
Life of this patent
Estimating the term…
Abstract
The invention relates to an isolated nucleic acid comprising two operatively linked binding sites for HIV Rev protein, the sites comprising a nucleation motif and an oligomerization motif, wherein the nucleic acid binds Rev protein monomers with a higher degree of cooperativity than wild-type RRE.
Claims17
An isolated nucleic acid comprising two operatively linked binding sites for HIV Rev protein, said sites comprising a nucleation motif and an oligomerization motif, wherein said nucleic acid binds Rev protein monomers with a higher degree of co-operativity than the wild-type RRE.
Dependencies are inferred from the claim text.