Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds

A polymeric fluorophenyl hydroxylamine resin compound of formula

• wherein
• is a solid support;
• A is absent or a group of formula —X1—Z— wherein
• X1 is —CHR— or —CHR—Y—CO—(CH2)n— wherein R is H, alkyl, phenyl, or phenyl substituted with —H, alkyl, alkoxy, halogen, nitrile or —NO2,
• R28, R29, and R30 are ring system substituents, or R28 and R29 taken together with the carbon atoms through which they are linked form a 6 membered aryl or a 5 to 6 membered heteroaryl,
• Y is —O— or —NH—,
• n is an integer from 1 to 6, and
• Z is —O— or —NH—;
• R3 and R4 are independently —H, alkyl, phenyl, or phenyl substituted with one or more substituents selected from alkyl, alkoxy, halogen nitrile and —NO2;
• and
• P1 is H or an amine protecting group.