Method for producing optically active 1-(4-t-butylphenyl)-5-oxo-3-pyrrolidine carboxylic acid and/or an enantiomeric ester thereof
AssigneesNagase & Co., Ltd., Taiho Pharmaceutical Co., Ltd.
InventorsKoutaro Ohtsuka, Shunji Kamiyama, Masafumi Moriwaki
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Abstract
A method for producing an optically active 1-(4-t-butylphenyl)-5-oxo-3-pyrrolidine carboxylic acid and/or an enantiomeric ester thereof which includes treating an ester of (±)-1-(4-t-butylphenyl)-5-oxo-3-pyrrolidine carboxylic acid with an esterase derived from Bacillus brevis 042-24 (FERM BP-5872).
Claims5
A method for producing an optically active 1-(4-t-butylphenyl)-5-oxo-3-pyrrolidine carboxylic acid and/or an enantiomeric ester thereof comprising treating an ester of (±)-1-(4-t-butylphenyl)-5-oxo-3-pyrrolidine carboxylic acid with an esterase derived from Bacillus brevis 042-24 FERM BP-5827.
Dependencies are inferred from the claim text.