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US 6,389,313 B1Granted
Laser probes for drug permeation
OwnerKevin S. Marchitto, Stephen T. Flockinventors
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Abstract
The present invention provides an optical device/method for enhancing local administration of pharmaceutical compounds and/or collection of biomaterials. Such device/method is used for various situations which require high concentrations of drugs that are delivered locally.
Claims28
An optical device employing radiant energy to enhance local delivery of a compound to or from a subject, said optical device comprising:
- an optical probe with a tip;
- a source for radiant energy;
- a catheter for delivering a compound to or from said tip;
- a catheter for delivering radiant energy to said tip;
- and
- a means to observe placement of said tip;
- wherein said optical device is designed to enhance delivery of a compound by a method selected from the group consisting of applying optical pressure to generate propagating pressure waves in a medium to increase diffusion of a compound through said medium;
- applying optical pressure to a compound to directly drive said compound through membranes and tissue by optical propulsion;
- creating an optical trap to drive diffusion of a compound;
- and, directly applying radiant energy to tissue to increase the permeability of said tissue to a compound.
7 more elements
Dependencies are inferred from the claim text.