Confocal laser scanning microscope
AssigneeLeica Microsystems Heidelberg GmbH
InventorsWerner Knebel, Heinrich Ulrich
Life of this patent
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Abstract
A confocal laser scanning microscope having at least one laser light source (1) for illuminating a specimen (2) and at least one detector (4) for detecting the detected light (3) coming from the specimen is characterized, in order to expand CLSM applications with regard to the use of light sources with lower acquisition and operating costs, in that an additional light source (5, 8) is provided that is not a single-mode (TEM00) laser light source.
Claims43
A confocal laser scanning microscope defining a beam path comprises at least one laser light source (1) for illuminating a specimen (2), at least one detector (4) for detecting light (3) coming from the specimen;
- an additional light source (5, 8) that is not a single-mode (TEM00) laser light source;
- and system parameter adjustment means for influencing signal-to-noise ratio in the image data of the specimen.
A confocal laser fluorescence microscope comprises at least one laser light source (1) for illuminating a specimen (2), at least one detector (4) for detecting light (3) coming from the specimen;
- an additional light source (5, 8) that is not a single-mode (TEM00) laser light source;
- and system parameter adjustment means for influencing signal-to-noise ratio in the image data of the specimen.
Dependencies are inferred from the claim text.