Salts of opioid analgesics, particularly morphine, and methods of using same
AssigneeWest Pharmaceutical Services Drug Delivery & Clinical Research Centre Limited
InventorsLisbeth Illum, Peter Watts, Ian Lafferty, Alan Smith
Life of this patent
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Abstract
The methane sulphonate salt of morphine and compositions thereof have medicinal uses, particularly in the treatment of pain. Compositions comprising a methane sulphonate salt of an opioid analgesic also have medicinal uses, adapted for nasal delivery.
Claims12
A composition adapted for nasal delivery, comprising a methane sulphonate salt of an opioid analgesic.
A method of treating pain, comprising administering to the nose of a patient suffering from pain an effective amount of a methane sulphonate salt of an opioid analgesic.
A method of treating pain, comprising administering to the nose of a patient suffering from pain an effective amount of the methane sulphonate salt of morphine.
A method of preparation of a solution formulation of morphine adapted for nasal administration, the method comprising neutralizing a suspension of morphine base in water with methane sulphonic acid.
A pharmaceutical composition adapted for nasal administration comprising the methane sulphonate salt of morphine.
A nasal drug delivery device, containing as a drug a methane sulphonate salt of an opioid analgesic.
Dependencies are inferred from the claim text.