Drug of improving optic nerve head circulation disorder
AssigneeAkzo Nobel N.V.
InventorsHideaki Hara, Masamitsu Shimazawa, Yasushi Iwakura, Tetsuya Sugiyama
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Abstract
A novel drug for improving the circulation in the optic nerve head, which comprises as an active ingredient Lomerizine (I): or a pharmaceutically acceptable acid addition salt. The optic nerve head circulation improving drug of this invention can increase the blood flow in the optic nerve head with no or little systemic side effects such as hypotensive activity or heart rate increasing activity and is useful particularly for the treatment of normal tension glaucoma.
Claims18
A method for improving the circulation in the optic nerve head, which comprises administering orally an effective amount of Lomerizine or a pharmaceutically acceptable acid addition salt thereof to a subject in need thereof.
A method for improving the circulation in the optic nerve head, which comprises injecting an effective amount of Lomerizine or a pharmaceutically acceptable acid addition salt thereof to a subject in need thereof.
A method for treating normal tension glaucoma, comprising the step of administering orally an effective amount of Lomerizine or a pharmaceutically acceptable acid addition salt thereof to a patient suffering from normal tension glaucoma.
A method for treating normal tension glaucoma, comprising the step of injecting an effective amount of Lomerizine or a pharmaceutically acceptable acid addition salt thereof to a patient suffering from normal tension glaucoma.
Dependencies are inferred from the claim text.