US 6,387,883 B1 · Method for the prevention and treatment of cachexia and anorexia

Abstract

The present invention relates to methods and nutritional compositions for the prevention and treatment of cachexia and anorexia. The methods of the invention comprise administering a composition comprising effective amounts of ω-3 fatty acids such as alpha-linolenic acid, stearidonic acid, eicosapentaenoic acid, docosapentaenoic acid, docosahexaenoic acid or mixtures thereof; of branched-chain amino acids valine, leucine, isoleucine or mixtures thereof; with or without reduced levels of tryptophan and 5-hydroxytryptophan; and of antioxidant system selected from the group comprising beta-carotene, vitamin C, vitamin E, selenium, or mixtures thereof.

Claims18

Dependent claims

A liquid nutritional composition comprising:

(a) at least 450 mg per liter of ω-3 fatty acids, wherein the weight ratio of ω-6 fatty acids to ω-3 fatty acids is from about 0.1 to about 1.0, and;
(b) an antioxidant system comprising at least one ingredient selected from the group consisting of beta-carotene, vitamin C, vitamin E and selenium.

Dependencies are inferred from the claim text.

Facts

Application

09/642,630Filed 18 Aug 2000 · continuation

Priority

25 Apr 1996

Granted

14 May 2002

Term ends

Not estimatedThe source records don’t support an estimate.

Classification24 codes

A61K 9/0029
Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in…
A23L 33/12
Fatty acids or derivatives thereof; Fats or oils: fatty acids or derivatives thereof
A23L 33/16
Using additives: inorganic salts, minerals or trace elements
A23L 33/175
Amino acids, peptides or proteins: amino acids

Family

Application08/635,179Parent of this continuation-in-part · filed 25 Apr 1996

Application08/842,454Parent of this division · filed 24 Apr 1997

Application09/479,550Parent of this continuation · filed 7 Jan 2000

US 6,326,355 B1Parent of this continuation

Application09/479,550Parent of this division

US 6,077,828 AParent of this division

Application08/842,454Parent of this continuation-in-part

US 6,387,883 B1This patent

From the US filing history. Foreign family members aren’t listed.

Method for the prevention and treatment of cachexia and anorexia

Life of this patent

Method for the prevention and treatment of cachexia and anorexia

Life of this patent

Abstract

Claims18