Process for producing indolmycin
AssigneeTakeda Chemical Industries, Ltd.
InventorsAkihiko Naotsuka, Motoo Izawa, Ken-ichiro Miyagawa
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Abstract
A microorganism having indolmycin-producing ability and tryptophan analogue resistance is provided, and indolmycin or its salt can be produced efficiently by cultivating such microorganism in a medium to produce and accumulate indolmycin or its salt in the culture broth followed by recovering a product.
Claims4
An isolated microorganism of Streptomyces griseus having all the identifying characteristics of Streptomyces griseus strain 5FW-1-226-9, deposited with the NIBH, having an accession number of FERM BP-6336.
An isolated microorganism of Streptomyces griseus having all the identifying characteristics of Streptomyces griseus strain 5FW-2-8-7, deposited with the NIBH, having an accession number of FERM BP-6337.
An isolated microorganism of Streptomyces griseus having all the identifying characteristics of Streptomyces griseus strain 6FW-1-8-5, deposited with the NIBH, having an accession number of FERM BP-6381.
A method for producing indolmycin or its salt comprising cultivating a microorganism of Streptomyces griseus strain 5FW-1-226-9;
- Streptomyces griseus strain 5FW-2-8-7;
- or Streptomyces griseus strain 6FW-1-8-5 in a medium to allow indolmycin or its salt to be accumulated in the culture broth;
- and then, recovering indolmycin.
Dependencies are inferred from the claim text.