Motor proteins and method for their use
AssigneeCytokinetics, Inc.
InventorsChristophe Beraud, Richard Freedman
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Abstract
The invention provides isolated nucleic acid and amino acid sequences of HsKif9, antibodies to HsKif9, methods of screening for HsKif9 modulators using biologically active HsKif9, and kits for screening for HsKif9 modulators.
Claims13
An isolated microtubule motor protein, having microtubule stimulated ATPase activity wherein the protein comprises an amino acid sequencing having greater than 95% amino acid sequence identity to SEQ ID NO:2 as measured using BLAST sequence comparison algorithm.
An isolated protein comprising an amino acid sequence of SEQ ID NO:2 or SEQ ID NO:4.
An isolated protein, having microtubule stimulated ATPase activity wherein the protein comprises an amino acid sequence having greater than 98% amino acid sequence identity to SEQ ID NO:4 as measured using a sequence comparison algorithm.
Dependencies are inferred from the claim text.