Sparc fusion protein and method for producing the same
AssigneeSecretary of Agency of Industrial Science and Technology
InventorMitsushi Ikemoto
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Abstract
The present invention provides a secreted protein acidic and rich in cysteine (SPARC) fusion protein obtainable by fusing SPARC to thioredoxin; a nucleic acid encoding the fusion protein; a recombinant vector capable of expressing the fusion protein, a method for producing and purifying the fusion protein; and a research reagent or pharmaceutical composition comprising the fusion protein as an active ingredient. In particular, the present invention relates to the use of a thioredoxin SPARC fusion protein for basic research in neurobiology and/or to its use for treating various neuropathologies.
Claims9
The isolated fusion protein as set forth in SEQ ID NO:2, wherein said fusion protein inhibits nerve cell adhesion to plastic.
An isolated nucleic acid comprising nucleotide 5209 through nucleotide 6609 of SEQ ID NO:1.
Dependencies are inferred from the claim text.