Use of lipids as adjuvents in the production of solid medicinal forms by the melt extrusion process

A process for producing a solid pharmaceutical composition in tablet form by melt extrusion, which process consists essentially of

• mixing an active ingredient, a water-soluble thermoplastic matrix polymer and a lipid;
• heating the mixture until a solvent-free, polymer melt is formed;
• extruding the melt into a tabletting molding calender;
• allowing the melt to cool;
• and
• removing the formed solid pharmaceutical composition in the form of a tablet from the molding calender;
• wherein the lipid is used in amounts of 1-5% of the total weight of the composition and functions as a mold release agent and lubricant.