Polypeptides from mycrobacterium paratuberculosis
AssigneeInnogenetics N.V.
InventorsCarlo Cocito, Marc Coene, Myriam De Kesel, Philippe Gilot
Life of this patent
Estimating the term…
Loading patent…
AssigneeInnogenetics N.V.
InventorsCarlo Cocito, Marc Coene, Myriam De Kesel, Philippe Gilot
Estimating the term…
The invention relates to a polypeptide containing in its polypeptidic chain: the amino acid sequence of 101 amino acids of FIG. 8, or a fragment of this sequence, this fragment being such that it is liable to be recognized by antibodies also recognizing the abovesaid sequence of 101 amino acids, but it is not recognized by antibodies respectively raised against M. bovis, M. avium, M. phlei and M. tuberculosis, and possibly against M. leprae, M. intracellulare, M. scrofulaceum, M. fortuitum, M. gordonae and M. smegmatis; it is liable to generate antibodies which also recognize the abovesaid sequence of 101 amino acids but which do not recognize M. bovis, M. avium, M. Phlei and M. smegmatis; it reacts with the majority of sera from cattle suffering from Johne's disease; or the polypeptidic sequences resulting from the modification by substitution and/or by addition and/or by deletion of one or several amino acids in so far as this modification does not alter the above-mentioned properties.
A biologically pure polypeptide consisting of the amino acid sequence of SEQ ID NO 5, or a fragment thereof, wherein said fragment:
An isolated polypeptide consisting of any of the following sequences:
A fusion protein consisting of the amino acid sequence represented in (SEQ ID NO 9).
Dependencies are inferred from the claim text.