US 6,387,327 B1Granted

Apparatus for the preparation and the performance of sedimentation velocity tests on organic liquids and other substances

AssigneeDiesse Diagnostica Senese S.r.l.

InventorsAntonio Ricci, Francesco Cocola

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Abstract

On a base structure (101, 103), an assembly (104) oscillates about a horizontal axis (X—X) between two limit positions; on said assembly, a rotor (106) is capable of rotating about an axis (Y—Y) of rotation orthogonal to said horizontal axis (X—X) and has a ring of seats (121) for test tubes (1); an actuator (145) moves said assembly into a position with the axis of rotation (Y—Y) roughly horizontal, to carry out an agitation stage, and into a position with the axis of rotation (Y—Y) vertical, to carry out, before the reading stage, a centrifugation stage. The ring of seats (121) for test tubes has the test tubes (1) oriented, in the vertical position of said axis of rotation (Y—Y), with their bottom facing downwards and outwards.

Claims19

Dependent claims

Apparatus for preparation and performance, in times of less than 10 minutes, of analysis of a sedimentation velocity type on liquids which have to be agitated in test tubes, comprising:

an assembly, on a base structure, which assembly oscillates about a horizontal oscillation axis between two limit positions, a rotor on said assembly, which rotor is capable of rotating about a rotation axis orthogonal to said horizontal axis a ring of seats for test tubes on said rotor, which seats are arranged symmetrically about said rotation axis, means of moving said assembly into a position with the rotation axis substantially horizontal to perform agitation when said rotor is rotated, and into a position with the rotation axis vertical to carry out a reading stage, optical reading means, in a reading station, for optical reading along the test tube which arrives in said station by intermittent movements of said rotor when it is arranged with the rotation axis oriented vertically each of said seats for the test tubes have a connection which oscillates on the rotor about a tangential axis and tends to adopt, by gravity, a position parallel to the rotation axis of the rotor when the latter is vertical and moved in order to bring the test tubes consecutively to the reading station, the seats and the test tubes adopting, by centrifugal effect, an inclined position during fast rotation, until they are even orthogonal to said rotation axis;
in that on the oscillating assembly, guide members connected to said assembly and movably positioned on said assembly to contact the test tubes along an upper trajectory of the test tubes in the position of the rotor with the rotation axis essentially horizontal, during agitation, to put the test tubes in an inclined position with their bottom facing upwards;
and in that said rotor is rotatable by motor means at an agitation speed for agitation of the fluid with the rotation axis horizontal, and in addition to intermittent motion in the position with the axis of rotation vertical for consecutive positioning of the test tubes in the reading station, said motor means rotating said rotor at a centrifugal speed with said rotation axis substantially vertical in order to obtain a centrifugation effect in the liquid of the test tubes and therefore accelerated sedimentation, after agitation and before the reading stage.

An apparatus for analysis of sedimentation rate on agitated liquids in containers, the apparatus comprising:

a base structure;
an assembly pivotally mounted on said base structure about an oscillation axis between first and second positions;
a rotor rotatably mounted on said assembly about a rotation axis orthogonal to said oscillation axis;
a plurality of seats for receiving the containers, each of said seats having a tangential pivotal connection to said rotor for being pivotally connected to said rotor about a seat axis tangential to rotation of said rotor about said rotation axis;
an actuator moving said assembly and said rotor into said second position to have rotation of said rotor cause agitation of the liquids in the containers, said actuator moving said assembly and said rotor into said first position for measuring the sedimentation rate;
a reading station for optical reading along the containers;
a drive for rotating said rotor at an agitation speed when said assembly and said rotor are in said second position for agitating the liquids in the container, said drive rotating said rotor at a centrifugal speed when said assembly and said rotor are in said first position to accelerate sedimentation;
a guide member arranged on said assembly and movable into and out of contact with the containers to selectively oscillate the containers about said seat axis when said rotor is rotating in said second position.

5 more elements

An apparatus for analysis of sedimentation rate on agitated liquids in containers, the apparatus comprising:

a base structure;
an assembly pivotally mounted on said base structure about an oscillation axis between first and second positions;
a rotor rotatably mounted on said assembly about a rotation axis orthogonal to said oscillation axis;
a plurality of seats for receiving the containers, each of said seats having a tangential pivotal connection to said rotor for being pivotally connected to said rotor about a seat axis tangential to rotation of said rotor about said rotation axis;
an actuator moving said assembly and said rotor into said second position to have rotation of said rotor cause agitation of the liquids in the containers, said actuator moving said assembly and said rotor into said first position for measuring the sedimentation rate;
a reading station for optical reading along the containers;
a drive for rotating said rotor at an agitation speed when said assembly and said rotor are in said second position for agitating the liquids in the container, said drive rotating said rotor at a centrifugal speed when said assembly and said rotor are in said first position to accelerate sedimentation;
said oscillation axis of said assembly is substantially horizontal;
said first position of said assembly holds said rotational axis substantially vertical;
said second position of said assembly holds said rotational axis substantially horizontal and moves the containers in a vertical trajectory during rotation of said rotor in said second position;
said tangential pivotal connection of said seats cooperate with gravity to position a longitudinal axis of the containers parallel to said rotation axis in said first position of said assembly and said rotor when said rotor is stopped, and to incline the longitudinal axis of the containers to said rotation axis when said rotor is rotated at said centrifugal speed;
said drive rotates said rotor intermittently to bring the containers consecutively to said reading station when said rotor and said assembly are in said first position;
a guide member arranged on said assembly and movable into contact with the containers along an upper trajectory of the containers when rotating in said second position of said rotor, said guide member moving the containers into a position with a bottom of the containers facing upward;
said centrifugal speed is faster than said agitation speed;
said drive rotates said rotor at said centrifugal speed after rotation at said agitation speed and before said rotor brings the containers to said reading station;
said seats are arranged in a ring symmetrically about said rotation axis.

13 more elements

Dependencies are inferred from the claim text.