Back to results
US 6,381,562 B2Granted
Configurable bio-transport system simulator
OwnerJohn A. Keaneinventor
Life of this patent
Estimating the term…
Abstract
A method of simulating a bio-transport system comprising: (a) characterizing one or more elements to represent a bio-transport system of an organism or a portion thereof; (b) constructing one or more mathematical representations that model one or more bio-transport dynamics for each element based on the characterization of the elements to form a configured simulation model; (c) initializing the configured simulation model; (d) executing the configured simulation model to obtain bio-transport dynamics data for one or more elements; and (e) outputting information to a user based on at least a portion of the bio-transport dynamics data.
Claims32
A method of simulating a bio-transport system comprising:
- characterizing a plurality of elements to represent a bio-transport system of at least a portion of an organism;
- configuring a simulation model by constructing a plurality of mathematical representations that model bio-transport dynamics for each element based on the characterization of said elements, wherein said bio-transport dynamics include at least:
- flow of a fluid in said bio-transport system, the flow at a particular element being modeled by a first mathematical representation which at least conserves momentum and conserves energy of essentially all of said elements;
- and
- concentration of at least one entity within said fluid, the concentration of said entity at a particular element being modeled by a second mathematical representation which is a function of flow as determined by said first mathematical representation, and of concentration of said entity in essentially all of said elements;
- initializing the configured simulation model;
- executing said configured simulation model to obtain bio-transport dynamics data for one or more elements, wherein bio-transport dynamics data comprises at least flow data of said fluid at a particular element, and concentration data of said entity in said fluid at a particular element;
- and
- outputting information to a user based on at least a portion of said bio-transport dynamics data.
6 more elements
A method of simulating a transport system comprising:
- providing a constructed simulation model comprising:
- a plurality of elements characterized to represent at least a portion of a bio-transport system;
- at least one model having one or more mathematical representations of one or more bio-transport dynamics for each element, said mathematical representations being constructed based on the characterization of said elements, wherein said bio-transport dynamics include at least:
- flow of a fluid in said bio-transport system, the flow at a particular element being modeled by a first mathematical representation which at least conserves energy of essentially all of said elements;
- and
- concentration of at least one entity within said fluid, the concentration of said entity at a particular element being modeled by a second mathematical representation which is a function of flow as determined by said first mathematical representation, and of concentration of said entity in essentially all of said elements;
- initializing said constructed simulation model;
- executing said configured simulation model to obtain bio-transport dynamics data for one or more elements, wherein said bio-transport dynamics data comprises at least flow data of said fluid at a particular element, and concentration data of said entity in said fluid at a particular element;
- and
- outputting information to a user based on at least a portion of said bio-transport dynamics data.
7 more elements
A computer system for simulating a transport system comprising:
- a processor;
- a user interface operatively connected to the processor for receiving input from and conveying output to a user;
- and
- memory operatively connected to the processor and containing instructions for constructing and/or executing the simulation model;
- wherein constructing said simulation model comprises
- (a) receiving construction data characterizing a plurality of elements to represent a bio-transport system or a portion thereof;
- (b) constructing one or more mathematical representations that model bio-transport dynamics for each element based on the data characterizing said element to form a configured simulation model, wherein said bio-transport dynamics include at least:
- flow of a fluid in said bio-transport system, the flow at a particular element being modeled by a first mathematical representation which at least conserves momentum and conserves energy of essentially all of said elements;
- and
- concentration of at least one entity within said fluid, the concentration of said entity at a particular element being modeled by a second mathematical representation which is a function of flow as determined by said first mathematical representation, and of concentration of said entity is essentially all of said elements;
- and
- wherein executing said simulation model comprises (a) initialing said configured simulation model;
- and (b) executing said configured simulation model to obtain bio-transport dynamic data for one or more elements, wherein said bio-transport dynamics data comprises at least flow data of said fluid at a particular element, and concentration data of said entity in said fluid at a particular element.
10 more elements
A computer-readable medium comprising:
- instructions for enabling a computer-based system to construct and/or execute the simulation model;
- wherein construction said simulation model comprises (a) receiving data characterizing a plurality of elements to represent a bio-transport system or a portion thereof;
- (b) constructing one or more mathematical representations that model bio-transport dynamics for each element based on the data characterizing said elements to form a configured simulation model,
- wherein said bio-transport dynamics include at least:
- flow of a fluid in said bio-transport system, the flow at a particular element being modeled by a first mathematical representation which at least conserves momentum and conserves energy of essentially all of said elements;
- and
- concentration of at least one entity within said fluid, the concentration of said entity at a particular element being modeled by a second mathematical representation which is a function of flow as determined by said first mathematical representation, and of concentration of said entity in essentially all of said elements;
- and
- wherein executing said simulation model comprises (a) initialing said configured simulation model;
- and (b) executing said configured simulation model to obtain bio-transport dynamic data for one or more elements, wherein said bio-transport dynamics data comprises at least flow data of said fluid at a particular element, and concentration data of said entity in said fluid at a particular element.
7 more elements
Dependencies are inferred from the claim text.