Back to results
US 6,376,653 B1Granted
Tie2 antagonist antibodies
AssigneeSmithKline Beecham Corporation
InventorsStephen D. Holmes, Connie L. Erickson-Miller, James D. Winkler
Life of this patent
Estimating the term…
Abstract
Tie2 receptor antagonist antibodies, their use in inhibiting angiogenesis and other uses are disclosed.
Claims6
An antibody comprising a heavy chain variable region and a light chain variable region wherein the heavy chain variable region comprises CDRs having the amino acid sequences shown in SEQ ID NOs:
- 5, 6 and 7 and the light chain variable region comprises CDRs having the amino acid sequences shown in SEQ ID NOs:
- 8,9 and 10.
An antibody comprising a heavy chain variable region polypeptide as set forth in SEQ ID NO:
- 2 and a light chain variable region polypeptide as set forth in SEQ ID NO:
- 4.
Dependencies are inferred from the claim text.