Recombinant vaccinia viral vectors
AssigneeArizona Board of Regents
InventorsBertram Jacobs, Jeffrey Langland, Sangeetha Vijaysri
Life of this patent
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Abstract
The present invention provides recombinant vaccinia virus in which the E3L gene is replaced by a gene encoding an E3L homolog from the orf virus. Compositions comprising the recombinant vaccinia virus and methods of use thereof are also provided.
Claims7
Vaccinia virus in which the E3L gene is replaced by a gene encoding an E3L homolog from the orf virus.
An expression vector comprising a vaccinia virus in which the E3L gene is replaced by a gene encoding an E3L homolog from the orf virus wherein said vector further comprises exogenous DNA operably linked to regulatory elements that control expression of said exogenous DNA.
A method of making a recombinant gene product comprising subjecting an expression vector comprising a vaccinia virus in which the E3L gene is replaced by a gene encoding an E3L homolog from the orf virus wherein said vector further comprises exogenous DNA operably linked to regulatory elements that control expression of said exogenous DNA to conditions whereby said recombinant gene product is expressed.
Recombinant vaccinia virus WR orf E3L.
Dependencies are inferred from the claim text.