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US 6,361,958 B1Granted
Biochannel assay for hybridization with biomaterial
AssigneeMotorola, Inc.
InventorsChan-Long Shieh, Barbara Foley, Huinan Yu, Vi-En Choong
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Abstract
The invention relates to a microfluidic device with microchannels that have separated regions which have a member of a specific binding pair member such as DNA or RNA bound to porous polymer, beads or structures fabricated into the microchannel. The microchannels of the invention are fabricated from plastic and are operatively associated with a fluid propelling component and detector.
Claims24
A microfluidic device comprising:
- i) a first microchannel;
- ii) at least a first entrance port and at least a first exit port for the transportation of at least one test sample;
- iii) a fluid propelling component that controls the flow rate of said test sample;
- iv) a detector that detects a binding pair in said test sample;
- and
- v) a recirculating arm that recirculates said test sample back into said first microchannel;
- wherein said first microchannel comprises a plurality of spacially distinct regions upon which specific binding pair members are immobilized.
4 more elements
Dependencies are inferred from the claim text.