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US 6,350,471 B1Granted
Tablet comprising a delayed release coating
AssigneePharma Pass LLC
InventorPawan Seth
Life of this patent
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Abstract
The invention provides a delayed release tablet, comprising: (i) a core comprising an active ingredient selected from the group consisting of oxybutynin hydrochloride, propranolol hydrochloride, buspiron hydrochloride, niacin, cetirizin hydrochloride, cerivastin sodium, metoprolol fumarate, and alendronate sodium., and conventional excipients; and (ii) a coating consisting essentially of a water-insoluble, water-permeable film- forming polymer, a plasticizer and a water-soluble polymer.
Claims13
A delayed release tablet comprising:
- (i) a core comprising an active ingredient selected from the group consisting of oxybutynin hydrochloride, propranolol hydrochloride, buspiron hydrochloride, niacin, cetirizin hydrochloride, cerivastin sodium, metoprolol fumarate, and alendronate sodium, and conventional excipients;
- and
- (ii) a coating consisting essentially by weight, based on the coating weight, of 20 to 85% of a water-insoluble, water-permeable film-forming polymer, of 10 to 75% of a water-soluble polymer and 5 to 30% of a plasticizer, exhibiting a dissolution profile such that after 2 hours, from 5 to 40% of the active ingredient is released, after 4 hours, from 10 to 60% of the active ingredient is released, after 12 hours, from 50 to 98% of the active ingredient is released, after 24 hours, more than 80% of the active ingredient is released.
Dependencies are inferred from the claim text.