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US 6,348,318 B1Granted
Methods for concentrating ligands using magnetic particles
AssigneeBiosite Diagnostics, Inc.
InventorGunars E. Valkirs
Life of this patent
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Abstract
This invention provides methods, compositions and kits for concentrating target ligands, including microorganisms, from samples, including biological samples. The methods involve the use of magnetic particles to concentrate the target analytes. Also provided are methods, compositions and kits for detecting the presence of target ligands in samples.
Claims15
A kit for detecting a target analyte in a sample, the kit comprising:
- a) a target analyte binding moiety that is capable of specifically binding the target analyte;
- b) a plurality of magnetically responsive particles to which are attached a plurality of capture moieties that are capable of reversibly binding the target analyte binding moiety;
- and
- c) a detection moiety that is capable of binding to the target analyte binding moiety or to a hapten present on the target analyte binding moiety.
1 more element
Dependencies are inferred from the claim text.