US 6,335,446 B1 · Quinolinium- and pyridinium-based fluorescent dye compounds

Abstract

The present invention relates to quinolinium- and pyridinium-based fluorescent dyes. The dyes are useful for staining proteins in solution, in gels and on solid supports. The dyes of the invention exhibit higher fluorescence emission than known compounds when bound to proteins and also exhibit improved contrast of fluorescence intensity between their protein-bound and unbound states.

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Facts

Application

09/412,168Filed 5 Oct 1999

Granted

1 Jan 2002

Term ends

Not estimatedThe source records don’t support an estimate.

Classification7 codes

C07D 213/57
Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals: nitriles
C07D 213/38
Radicals substituted by singly-bound nitrogen atoms: having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
C07D 215/12
Having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring…:…
C09B 23/0058
The substituent being a COOH and/or a functional derivative thereof: the substituent being CN

Quinolinium- and pyridinium-based fluorescent dye compounds

Life of this patent

Abstract

Claims0

Quinolinium- and pyridinium-based fluorescent dye compounds

Life of this patent

Abstract

Claims0