US 6,335,331 B1 · Pseudopolymorphic forms of 2-[2-[4-[Bis (4-fluorophenyl) methyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride

Abstract

The present invention relates to new pseudopolymorphic forms of 2-[2-[4-[bis (4-fluorophenyl)methyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride, namely, anhydrous 2-[2-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride and 2-[2-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride monohydrate. It also relates to processes for the preparation of these pseudopolymorphic forms and to pharmaceutical compositions containing them.

Claims0

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Claims aren’t available for this document.

Facts

Application

09/800,665Filed 8 Mar 2001

Published

US 2001/0021712 A113 Sep 2001

Granted

1 Jan 2002

Term ends

Not estimatedThe source records don’t support an estimate.

Classification14 codes

C07D 295/088
With the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings: to…
A61P 11/00
Drugs for disorders of the respiratory system
A61P 11/02
Drugs for disorders of the respiratory system: nasal agents, e.g. decongestants
A61P 11/08
Drugs for disorders of the respiratory system: bronchodilators

Pseudopolymorphic forms of 2-[2-[4-[Bis (4-fluorophenyl) methyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride

Life of this patent

Abstract

Claims0

Pseudopolymorphic forms of 2-[2-[4-[Bis (4-fluorophenyl) methyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride

Life of this patent

Abstract

Claims0