US 6,335,199 B1 · Lipid compounds and compositions containing same used for the transfer of at least an active substance, in particular a polynucleotide, in a target cell and therapeutic use

Abstract

The present invention relates to lipid compounds of formula I, wherein said compounds are optionally in a cationic form and are optionally combined with one or more biologically acceptable anions. The present invention also relates to complexes comprising at least one cationic lipid compound of the formula I and an active substance comprising negative charges. The present invention further relates to methods of gene therapy using the complexes of the present invention.

Claims0

Dependent claims

Claims aren’t available for this document.

Facts

Application

09/171,845Filed 28 Oct 1998

Granted

1 Jan 2002

Term ends

Not estimatedThe source records don’t support an estimate.

Classification7 codes

C12N 15/88
Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation: using microencapsulation, e.g. using…
A61K 9/1272
Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers: comprising non-phosphatidyl surfactants as…
A61K 47/54
The non-active ingredient being a modifying agent: the modifying agent being an organic compound
A61K 47/543
The modifying agent being an organic compound: lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine

Lipid compounds and compositions containing same used for the transfer of at least an active substance, in particular a polynucleotide, in a target cell and therapeutic use

Life of this patent

Abstract

Claims0

Lipid compounds and compositions containing same used for the transfer of at least an active substance, in particular a polynucleotide, in a target cell and therapeutic use

Life of this patent

Abstract

Claims0