Vectors and viruses for use in gene therapy

Abstract

The present invention relates to a vector suitable for use in gene therapy, which comprises an expressible insert DNA which codes for the DNA binding domain of a poly(ADP-ribose)-polymerase or for an at least partially catalytically inactive poly(ADP-ribose)-polymerase. Furthermore, this invention concerns processes for the preparation of such a vector and viruses suitable for use in gene therapy.

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