Method for collecting interstitial fluid from the skin

Abstract

A carrier film has one or more openings or wells loaded with a meltable absorbing substance for absorbing laser energy. The carrier film has a clear film which covers one side of the opening containing the absorber substance and the open side of the opening in the carrier film is positioned adjacent to the skin and irradiated through the clear cover film by a laser beam. The melted laser energy absorbing substance is ejected to form a spot laying on the skin. After moving the carrier film, a laser beam impinges the spot thereby raising a tiny blister on the skin containing interstitial fluid. The interstitial fluid is collected for diagnosis and analysis. A method of making and loading the carrier film with a digitally operated dispenser of the type used for ink jet printing is disclosed. Special construction of the opening appears to enhance ejection.

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