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US 6,333,435 B1Granted
Process of synthesizing binaphthyl derivatives
AssigneeMerck & Co., Inc.
InventorsDongwei Cai, David L. Hughes, Sylvain Levac, Thomas R. Verhoeven
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Abstract
A process of synthesizing a compound of the formula 1: is disclosed, which comprises reacting a compound of the formula 2: with diphenylphosphine in the presence of an amine base and a nickel catalyst to produce a compound of formula 1.
Claims6
A compound represented by the formula:
- in substantially pure form or in racemic mixture.
A compound represented by the formula:
- in substantially pure form or in racemic mixture.
Dependencies are inferred from the claim text.