Synergistic combination of PDE inhibitors and adenylate cyclase agonists or guanyl cyclyse agonists
AssigneeByk Gulden Lomberg Chemische Fabrik GmbH
InventorChristian Schudt
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Abstract
A diseased state based on acute or chronic obstruction of vessels and/or bronchi, acute or chronic inflammation and/or edema formation is advantageously treated by the combined administration of a PDE inhibitor with either an adenylate cyclase agonist or a guanylate cyclase agonist to a subject in need of such therapy. Administration can be either concurrent or in either order.
Claims6
A method of therapeutic treatment of pulmonary hypertension which comprises administering an effective amount of medicament to a subject in need of such therapy, wherein the medicament comprises a combination of a) a PDE inhibitor with b) an adenylate cyclase agonist or a guanylate cyclase agonist, and wherein administration of a) and b) is either concurrent or in either order.
Dependencies are inferred from the claim text.