Compound and its use
AssigneeGlaxo Wellcome Inc.
InventorsLorraine Mary Edmeades, Nigel Arthur Griffith-Skinner, Derek Anthony Hill, Graham Thronton Hill, Terence William Packham
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Abstract
A method of testing the purity or stability to degradation of a sample of lamotrigine or a pharmaceutical dosage form comprising lamotrigine comprises assaying the said sample for the presence of a compound selected from 3-amino-6-(2,3-dichlorophenyl)-1,2,4-triazine-5-(4H)-one (compound A) and N-[5-amino-6-(2,3-dichlorophenyl)-1,2,4-triazine-3-yl]-2,3-dichlorobenzamide (compound B). A process for producing compound B, which is novel, is also disclosed.
Claims9
A method of testing the purity of a sample of lamotrigine or a pharmaceutical dosage form comprising lamotrigine, which method comprises assaying the said sample for the presence of N-[5-amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide.
A compound which is N-[5-amino-6-(2,3-dichlorophenyl)-1,2,4-triazine-3-yl)]-2,3-dichlorobenzamide of formula (B):
Dependencies are inferred from the claim text.