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US 6,333,020 B1Granted
Methods for treating AVM's using radio active compositions
AssigneeMicro Therapeutics, Inc.
InventorsGeorge Wallace, Richard J. Greff
Life of this patent
Estimating the term…
Abstract
Disclosed are methods for treating AVMs in a mammal by use of a radiation composition.
Claims15
A method for treating an arteriovenous malformation (AVM) in a mammal which method comprises:
- (a) selecting a fluidic composition comprising a biocompatible polymer, a biocompatible solvent which solubilizes said polymer and a water insoluble radioisotope wherein said biocompatible solvent is selected from the group consisting of dimethylsulfoxide, ethanol, ethyl lactate and acetone;
- and
- (b) injecting an effective amount of said composition into one or more vascular sites of said mammal which lead to or are within the AVM under conditions wherein a solid mass is formed which solid mass ablates at least part of the AVM wherein said solid mass comprises the water insoluble polymer and the radioisotope
- and further wherein the radioactivity of the radioisotope is employed in an amount effective to inhibit regrowth of the AVM and to further ablate the AVM.
1 more element
A method for treating an arteriovenous malformation (AVM) in a mammal which method comprises:
- (a) selecting a fluidic composition comprising a biocompatible polymer, dimethlysulfoxide which solubilizes said polymer and a water insoluble radioisotope;
- and
- (b) injecting an effective amount of said composition into one or more vascular sites leading to or within the AVM under conditions wherein a solid mass is formed which solid mass ablates at least part of the AVM
- wherein the radioactivity of the radioisotope is employed in an amount effective to inhibit regrowth of the AVM and to further ablate the AVM.
1 more element
Dependencies are inferred from the claim text.