Solid dose delivery vehicle and methods of making same
AssigneeQuadrant Holdings Cambridge Limited
InventorsBruce J. Roser, Jaap Kampinga, Camilo Colaco, Julian Blair
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Abstract
The present invention encompasses a solid dose delivery vehicle for ballistic administration of a bioactive material to subcutaneous and intradermal tissue, the delivery vehicle being sized and shaped for penetrating the epidermis. The delivery vehicle further comprises a stabilizing polyol glass loaded with the bioactive material and capable of releasing the bioactive material in situ. The present invention further includes methods of making and using the solid dose delivery vehicle of the invention.
Claims54
A device for the topical, subcutaneous, intradermal, or transdermal delivery of a therapeutic agent, wherein the device includes a solid dose delivery vehicle comprising a therapeutically effective amount of said therapeutic agent and a polyol.
A device for the topical, subcutaneous, intradermal, or transdermal delivery of a therapeutic agent, wherein the device includes a solid dose delivery vehicle comprising a therapeutically effective amount of said therapeutic agent and a polyol wherein said delivery of said therapeutic agent is via ballistic delivery.
A method for the topical, subcutaneous, intradermal or transdermal delivery of a therapeutic agent to a subject, wherein the agent is in the form of a solid dose delivery vehicle comprising a therapeutically effective amount of said therapeutic agent and a polyol.
A method for the topical, subcutaneous, intradermal or transdermal delivery of a therapeutic agent to a subject, wherein the agent is in the form of a solid dose delivery vehicle comprising a therapeutically effective amount of said therapeutic agent and a polyol, and wherein said transdermal delivery of said therapeutic agent is via ballistic delivery.
Dependencies are inferred from the claim text.