Method and kit for imaging and treating organs and tissues
AssigneeImmunomedics, Inc.
InventorMilton David Goldenberg
Life of this patent
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Abstract
Provided are methods and compositions for detecting and treating normal, hypoplastic, ectopic or remnant tissue, organ or cells in a mammal. The method comprises parenterally injecting a mammalian subject, at a locus and by a route providing access to above-mentioned tissue or organ, with an composition comprising antibody/fragment which specifically binds to targeted organ, tissue or cell. The antibody/fragment may be administered alone, or labeled or conjugated with an imaging, therapeutic, cytoprotective or activating agent.
Claims15
An immunological method of ablating a cell in a mammalian subject, the method comprising administering to the subject requiring ablation of a cell, a composition comprising an antibody or fragment specific to a hormone receptor or growth factor receptor on a cell targeted for ablation, wherein the antibody or fragment is conjugated to a chemical or radiation ablation agent.
Dependencies are inferred from the claim text.