Orally disintegrable tablets
AssigneeTakeda Chemical Industries, Ltd.
InventorsToshihiro Shimizu, Shuji Morimoto, Tetsuro Tabata
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AssigneeTakeda Chemical Industries, Ltd.
InventorsToshihiro Shimizu, Shuji Morimoto, Tetsuro Tabata
Estimating the term…
An orally disintegrable tablet, of the present invention, which comprises (i) fine granules having an average particle diameter of 400 μm or less, which fine granules comprise a composition coated by an enteric coating layer, said composition having 10 weight % or more of an acid-labile physiologically active substance and (ii) an additive, has superior disintegrability or dissolution in the oral cavity so that it can be used for treatment or prevention of various diseases, as an orally disintegrable tablet capable of being administered to the aged or children and easily administered without water. Also, because the tablet of the present invention contains fine granules having the average particle diameter such that it will not impart roughness in mouth, it can be administered easily without discomfort at the administration.
An orally disintegrable tablet which comprises
Fine granules having an average particle diameter of 400 μm or less, which comprise a composition coated by an enteric coating layer comprising a first component which is an enteric coating agent and a second component which is a sustained-release agent, said composition having (i) 25 weight % or more of an acid-liable physiologically active substance that is lansoprazole and (ii) a basic inorganic salt.
Dependencies are inferred from the claim text.