Curved introduction for mass spectrometry
AssigneeAnalytica of Branford, Inc.
InventorsBruce A. Andrien, Jr., Michael A. Sansone, Allan G. Burt, Craig M. Whitehouse
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Abstract
A single or multiple layer curved Electrospray sample introduction means has been configured in an Atmospheric Pressure Ion (API) source interfaced to a mass analyzer. Sample solutions introduced through curved or bent sample introduction Electrospray (ES) probes configured in an API source are sprayed from the ES probe tip at an angle which differs from centerline of the ES probe body. Single or multiple curved ES probes can be configured in an Atmospheric Pressure Ion source interfaced to mass analyzers. Curved ES probes can also be configured in an API source which includes Atmospheric Pressure Chemical ionization.
Claims59
An apparatus for producing ions from solution comprising:
- a. an Electrospray ion source with at least one Electrospray sample introduction probe;
- b. said Electrospray probe comprising a curved portion;
- c. said curved portion comprising at least one fluid channel.
An apparatus for producing ions from solutions comprising:
- a. an ion source operated substantially at atmospheric pressure which produces ions from solutions;
- b. at least one curved Electrospray probe through which at least one solution is introduced into said ion source;
- and
- c. at least one Atmospheric Pressure Chemical Ionization probe through which at least one solution is introduced into said ion source.
A method for producing ions from solution comprising the steps of:
- providing solution to an Electrospray ion source comprising at least one Electrospray sample introduction probe, said Electrospray probe comprising a curved portion, said curved portion comprising at least one fluid channel.
A method for producing ions from solutions comprising:
- operating an apparatus comprising an ion source, wherein said apparatus comprises at least one curved Electrospray probe, and wherein said apparatus further comprises at least one Atmospheric Pressure Chemical Ionization probe.
An apparatus for producing ions from solution comprising:
- an Electrospray ion source comprising at least one Electrospray sample introduction probe, said Electrospray probe comprising a curved portion, said curved portion comprising at least one fluid channel.
Dependencies are inferred from the claim text.