Prophylactic or therapeutic drug for renal diseases
AssigneeTakeda Chemical Industries, Ltd.
InventorsKohei Nishikawa, Yumiko Shibouta, Keiji Kubo
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AssigneeTakeda Chemical Industries, Ltd.
InventorsKohei Nishikawa, Yumiko Shibouta, Keiji Kubo
Estimating the term…
Prophylactic or therapeutic drugs for diabetic nephropathy or glomerulonephritis, comprising, as an active ingredient, a compound or salt thereof represented by formula (I) wherein R1 stands for H or an optionally substituted hydrocarbon residue; R2 stands for an optionally esterified carboxyl group; R3 stands for a group actually or potentially capable of forming an anion; X shows that the phenylene and phenyl groups bind to each other directly or through a spacer having an atomic chain length of two or less; n stands for 1 or 2; ring A stands for a benzene ring having an optional substituent in addition to R2; Y stands for a bond, —O—, —S(O)m—, wherein m stands for 0, 1 or 2, or —N(R4)— wherein R4 stands for H or an optionally substituted alkyl group are disclosed.
A method for tbe prophylaxis or treatment of diabetic nephropathy or glomerulonephritis in a mammal comprising the step of administering a pharmaceutically effective amount of a compound or salt thereof represented by formula (I′)
Dependencies are inferred from the claim text.