Method of using levocetirizine and pharmaceutical compositions containing the same for inducing sleep
AssigneeSchering Corporation
InventorPeter Martin
Life of this patent
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Abstract
Disclosed is a method of inducing sleep in a human suffering from a sleeping disorder comprising administering to the human a therapeutically effective amount of cetirizine hydrochloride once daily. Also disclosed is pharmaceutical compositions concerning the same.
Claims24
A method for inducing sleep in a human suffering from a sleeping disorder comprising administering to the human a therapeutically effective amount of levocetirizine or a pharmaceutically acceptable salt thereof once daily.
A method of inducing sleep in a human suffering from a sleep disorder comprising administering to the human a therapeutically effective amount of levocetirizine or a pharmaceutically acceptable salt thereof once daily by intranasal administration.
A method of inducing sleep in a human suffering from a sleeping disorder comprising administering to the human a therapeutically effective amount of levocetirizine or a pharmaceutically acceptable salt thereof once daily at least about 3 hours prior to a normal sleeping period.
A pharmaceutical composition for intranasal administration comprising an amount of levocetirizine or a pharmaceutically acceptable salt thereof that is sufficient to induce sleep in a human and an aqueous carrier comprising 70 to 90% by weight/volume of water;
- 0.10 to 5.00% by weight, volume of an aromatic alcohol;
- 0.01 to 0.3% by weight/volume of a non-mercurial antimicrobial preservative;
- 0 to 10% by weight/volume of a moisturizing agent;
- 0 to 10% by weight/volume of an antioxidant;
- 0 to 2.00% by weight/volume of a surfactant, a sufficient amount of a pharmaceutically acceptable buffer to maintain the pH of the composition within the range of about 3 to about 7;
- and QS water.
Dependencies are inferred from the claim text.