Method for inhibiting eukaryotic protein kinases
AssigneeTerragen Diversity, Inc.
InventorsJulian E. Davies, Barbara Waters, Geeta Saxena
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Abstract
A number of bacterial cultures were screened for the ability to inhibit sporulation using a strain Streptomyces 85E. Evaluations of the cultures which tested positive in this assay led to the discovery that lipopeptide biosurfactants such as surfactin and viscosin are effective inhibitors of eukaryotic protein kinase activity. Thus, a method for inhibiting eukaryotic protein kinase activity present in a sample or organism includes the step of adding to the sample or organism an effective inhibitory amount of a lipopeptide biosurfactant.
Claims8
A method for inhibiting a mammalian protein kinase present in a sample or organism comprising the step of adding to the sample or organism an effective inhibitory amount of a lipopeptide biosurfactant, wherein the lipopeptide biosurfactant inhibits sporulation of Streptomyces.
Dependencies are inferred from the claim text.