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US 6,319,897 B1Granted
Peptides which inhibit complement activation
OwnerJohn D. Lambris, Arvind K. Sahuinventors
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Abstract
Peptides capable of inhibiting complement activation are provided. Methods of inhibiting complement activation and complement-mediated tissue injury using these peptides are also provided. In addition, a method of producing compositions capable of inhibiting complement activation using these peptides is provided, along with the peptide analogs and peptidomimetics produced by the method.
Claims7
A cylclic peptide capable of inhibiting complement activation comprisuing the N-terminal cyclic region of a peptide of SEQ ID NO:
- 1 or comprising an amino acid sequence selected from the group consisting of SEQ ID NO:
- 2, SEQ ID NO:
- 13, SEQ ID NO:
- 15, SEQ ID NO:
- 20, SEQ ID NO:
- 21, and SEQ ID NO:
- 22.
4 more elements
Dependencies are inferred from the claim text.