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AssigneeRoche Diagnostics GmbH
InventorsRaghbir S. Bhullar, Christopher D. Wilsey, Jeffrey N. Shelton
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A capillary hematocrit separation structure is included within a housing having a fluid inlet port, a reaction region, and a capillary pathway connecting the inlet port and the reaction region. The capillary pathway is dimensioned so that the driving force for the movement of liquid through the capillary pathway arises from capillary pressure. A plurality of obstructions are fixed in the capillary pathway, each obstruction having a concave portion facing toward the vented reaction region on the down stream side of the obstructions as viewed with reference to a liquid flowing from the inlet port to the reaction region. The capillary pathway in a hematocrit separation structure for a single drop sample size includes about 105 obstructions, each obstruction including a concave portion having a volume of between about 10−4 to 10−5 μl for selectively receiving hematocrit.
An apparatus for separating hematocrit from a whole blood sample having a selected total volume, the sample including a partial volume of blood plasma and a partial volume of hematocrit, the apparatus comprising:
In a clinical diagnostic device comprising a housing having a fluid inlet port, a vented reaction region, and at least one capillary pathway connecting the inlet port and the reaction region and in which the driving force for the movement of liquid through the at least one capillary pathway arises from capillary pressure, an improvement comprising:
A method for detecting an analyte in blood plasma comprising the steps of:
Dependencies are inferred from the claim text.