Solid thermoformable controlled-release pharmaceutical composition

A solid controlled-release pharmaceutical composition, wherein the composition consists of a thermoformed mixture of at least one active ingredient and of one or more pH independent polymers selected from the group consisting of the polymethacrylates, the release of the active ingredient(s) being controlled solely by the nature of the polymethacrylate(s) used, by the amount thereof relative to the active ingredient(s), and by the technique of injection, coinjection, extrusion, or coextrusion employed in the manufacture of the composition at a temperature of 60° C. to 150° C.

A solid controlled-release pharmaceutical composition, wherein the composition consists of a thermoformed mixture of at least one active ingredient and of at least two pH independent polymers selected from the group consisting of the polymethacrylates, the release of the active ingredient(s) being controlled solely by the nature of the polymethacrylate(s) used, by the amount thereof relative to the active ingredient(s), and by the technique of injection, co-injection, extrusion, or co-extrusion employed in the manufacture of the composition.